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Plasticity of the inner cell mass in mouse blastocyst is restricted by the activity of FGF/MAPK pathway
In order to ensure successful development, cells of the early mammalian embryo must differentiate to either trophectoderm (TE) or inner cell mass (ICM), followed by epiblast (EPI) or primitive endoderm (PE) specification within the ICM. Here, we deciphered the mechanism that assures the correct orde...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680175/ https://www.ncbi.nlm.nih.gov/pubmed/29123210 http://dx.doi.org/10.1038/s41598-017-15427-0 |