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AIP limits neurotransmitter release by inhibiting calcium bursts from the ryanodine receptor

Pituitary tumors are frequently associated with mutations in the AIP gene and are sometimes associated with hypersecretion of growth hormone. It is unclear whether other factors besides an enlarged pituitary contribute to the hypersecretion. In a genetic screen for suppressors of reduced neurotransm...

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Detalles Bibliográficos
Autores principales: Chen, Bojun, Liu, Ping, Hujber, Edward J., Li, Yan, Jorgensen, Erik M., Wang, Zhao-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680226/
https://www.ncbi.nlm.nih.gov/pubmed/29123133
http://dx.doi.org/10.1038/s41467-017-01704-z