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Liprotides kill cancer cells by disrupting the plasma membrane

HAMLET (human α-lactalbumin made lethal to tumour cells) is a complex of α-lactalbumin (aLA) and oleic acid (OA) which kills transformed cells, while leaving fully differentiated cells largely unaffected. Other protein-lipid complexes show similar anti-cancer potential. We call such complexes liprot...

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Detalles Bibliográficos
Autores principales: Frislev, Henriette S., Boye, Theresa Louise, Nylandsted, Jesper, Otzen, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680231/
https://www.ncbi.nlm.nih.gov/pubmed/29123177
http://dx.doi.org/10.1038/s41598-017-15003-6