DNA methylation regulates TMEM16A/ANO1 expression through multiple CpG islands in head and neck squamous cell carcinoma

ANO1 is a calcium-activated chloride channel that is frequently overexpressed in head and neck squamous cell carcinoma (HNSCC) and other cancers. While ANO1 expression negatively correlates with survival in several cancers, its epigenetic regulation is poorly understood. We analyzed HNSCC samples fr...

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Detalles Bibliográficos
Autores principales: Finegersh, Andrey, Kulich, Scott, Guo, Theresa, Favorov, Alexander V., Fertig, Elana J., Danilova, Ludmila V., Gaykalova, Daria A., Califano, Joseph A., Duvvuri, Umamaheswar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680248/
https://www.ncbi.nlm.nih.gov/pubmed/29123240
http://dx.doi.org/10.1038/s41598-017-15634-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680248/
https://www.ncbi.nlm.nih.gov/pubmed/29123240
http://dx.doi.org/10.1038/s41598-017-15634-9

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