Hypoxia-induced reactive oxygen species mediate N-cadherin and SERPINE1 expression, EGFR signalling and motility in MDA-MB-468 breast cancer cells

One of the hallmarks of the tumour microenvironment is hypoxia resulting from increased oxygen consumption by proliferative cancer cells and altered vasculature. Hypoxic tension initiates various cellular signals and can drive epithelial to mesenchymal transition (EMT), a process important in cancer...

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Detalles Bibliográficos
Autores principales: Azimi, Iman, Petersen, Rosalie M., Thompson, Erik W., Roberts-Thomson, Sarah J., Monteith, Gregory R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680275/
https://www.ncbi.nlm.nih.gov/pubmed/29123322
http://dx.doi.org/10.1038/s41598-017-15474-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680275/
https://www.ncbi.nlm.nih.gov/pubmed/29123322
http://dx.doi.org/10.1038/s41598-017-15474-7

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