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Hypoxia-induced reactive oxygen species mediate N-cadherin and SERPINE1 expression, EGFR signalling and motility in MDA-MB-468 breast cancer cells
One of the hallmarks of the tumour microenvironment is hypoxia resulting from increased oxygen consumption by proliferative cancer cells and altered vasculature. Hypoxic tension initiates various cellular signals and can drive epithelial to mesenchymal transition (EMT), a process important in cancer...
Autores principales: | Azimi, Iman, Petersen, Rosalie M., Thompson, Erik W., Roberts-Thomson, Sarah J., Monteith, Gregory R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680275/ https://www.ncbi.nlm.nih.gov/pubmed/29123322 http://dx.doi.org/10.1038/s41598-017-15474-7 |
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