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The gene fmt, encoding tRNA(fMet)-formyl transferase, is essential for normal growth of M. bovis, but not for viability
Mycobacterium tuberculosis is a major health threat, necessitating novel drug targets. Protein synthesis in bacteria uses initiator tRNA(i) charged with formylated methionine residue. Deletion of the formylase gene, tRNA(fMet)-formyl transferase (fmt), causes severe growth-retardation in E. coli and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680289/ https://www.ncbi.nlm.nih.gov/pubmed/29123253 http://dx.doi.org/10.1038/s41598-017-15618-9 |