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A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells
There are presently no reliable ways to quantify endocrine cell mass (ECM) in vivo, which prevents an accurate understanding of the progressive beta cell loss in diabetes or following islet transplantation. To address this unmet need, we coupled RNA sequencing of human pancreatic islets to a systems...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680294/ https://www.ncbi.nlm.nih.gov/pubmed/29123178 http://dx.doi.org/10.1038/s41598-017-15417-2 |