A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells

There are presently no reliable ways to quantify endocrine cell mass (ECM) in vivo, which prevents an accurate understanding of the progressive beta cell loss in diabetes or following islet transplantation. To address this unmet need, we coupled RNA sequencing of human pancreatic islets to a systems...

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Detalles Bibliográficos
Autores principales: Balhuizen, Alexander, Massa, Sam, Mathijs, Iris, Turatsinze, Jean-Valery, De Vos, Jens, Demine, Stéphane, Xavier, Catarina, Villate, Olatz, Millard, Isabelle, Egrise, Dominique, Capito, Carmen, Scharfmann, Raphaël, In’t Veld, Pieter, Marchetti, Piero, Muyldermans, Serge, Goldman, Serge, Lahoutte, Tony, Bouwens, Luc, Eizirik, Decio L., Devoogdt, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680294/
https://www.ncbi.nlm.nih.gov/pubmed/29123178
http://dx.doi.org/10.1038/s41598-017-15417-2

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