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Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis

A high cell proliferation rate, invasiveness and resistance to chemotherapy are the main features of glioblastoma (GBM). GBM aggressiveness has been widely associated both with a minor population of cells presenting stem-like properties (cancer stem-like cells, CSCs) and with the ability of tumor ce...

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Detalles Bibliográficos
Autores principales: Giacomelli, Chiara, Daniele, Simona, Natali, Letizia, Iofrida, Caterina, Flamini, Guido, Braca, Alessandra, Trincavelli, M. Letizia, Martini, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680298/
https://www.ncbi.nlm.nih.gov/pubmed/29123181
http://dx.doi.org/10.1038/s41598-017-15360-2