Discordancy Partitioning for Validating Potentially Inconsistent Pharmacogenomic Studies

The Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE) are two major studies that can be used to mine for therapeutic biomarkers for cancers of a large variety. Model validation using the two datasets however has proved challenging. Both predictions and signatures...

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Detalles Bibliográficos
Autores principales: Rao, J. Sunil, Liu, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680312/
https://www.ncbi.nlm.nih.gov/pubmed/29123200
http://dx.doi.org/10.1038/s41598-017-15590-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680312/
https://www.ncbi.nlm.nih.gov/pubmed/29123200
http://dx.doi.org/10.1038/s41598-017-15590-4

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