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Discordancy Partitioning for Validating Potentially Inconsistent Pharmacogenomic Studies
The Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE) are two major studies that can be used to mine for therapeutic biomarkers for cancers of a large variety. Model validation using the two datasets however has proved challenging. Both predictions and signatures...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680312/ https://www.ncbi.nlm.nih.gov/pubmed/29123200 http://dx.doi.org/10.1038/s41598-017-15590-4 |