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Insights from mathematical modeling for convection-enhanced intraputamenal delivery of GDNF
Glial cell line-derived neurotrophic factor (GDNF) is a potential therapy for Parkinson’s disease (PD) promoting survival and functional recovery of dopaminergic neurons when delivered to the degenerated striatum. To study the aspects of intraputamenal delivery of GDNF, a mathematical model of recom...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680405/ https://www.ncbi.nlm.nih.gov/pubmed/28493093 http://dx.doi.org/10.1007/s11517-017-1650-x |