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Insights from mathematical modeling for convection-enhanced intraputamenal delivery of GDNF

Glial cell line-derived neurotrophic factor (GDNF) is a potential therapy for Parkinson’s disease (PD) promoting survival and functional recovery of dopaminergic neurons when delivered to the degenerated striatum. To study the aspects of intraputamenal delivery of GDNF, a mathematical model of recom...

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Detalles Bibliográficos
Autores principales:	Belova, Elena, Shaffer, Christopher L., Trapa, Patrick E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680405/ https://www.ncbi.nlm.nih.gov/pubmed/28493093 http://dx.doi.org/10.1007/s11517-017-1650-x

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