Heterogeneity in retinoblastoma: a tale of molecules and models

Retinoblastoma, an intraocular pediatric cancer, develops in the embryonic retina following biallelic loss of RB1. However, there is a wide range of genetic and epigenetic changes that can affect RB1 resulting in different clinical outcomes. In addition, other transformations, such as MYCN amplifica...

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Detalles Bibliográficos
Autores principales: Stenfelt, Sonya, Blixt, Maria K. E., All-Ericsson, Charlotta, Hallböök, Finn, Boije, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680409/
https://www.ncbi.nlm.nih.gov/pubmed/29124525
http://dx.doi.org/10.1186/s40169-017-0173-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680409/
https://www.ncbi.nlm.nih.gov/pubmed/29124525
http://dx.doi.org/10.1186/s40169-017-0173-2

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