Cargando…

STAT3-RXR-Nrf2 activates systemic redox and energy homeostasis upon steep decline in pO(2) gradient

Hypobaric hypoxia elicits several patho-physiological manifestations, some of which are known to be lethal. Among various molecular mechanisms proposed so far, perturbation in redox state due to imbalance between radical generation and antioxidant defence is promising. These molecular events are als...

Descripción completa

Detalles Bibliográficos
Autores principales: Paul, Subhojit, Gangwar, Anamika, Bhargava, Kalpana, Ahmad, Yasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680518/
https://www.ncbi.nlm.nih.gov/pubmed/29078168
http://dx.doi.org/10.1016/j.redox.2017.10.013