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STAT3-RXR-Nrf2 activates systemic redox and energy homeostasis upon steep decline in pO(2) gradient
Hypobaric hypoxia elicits several patho-physiological manifestations, some of which are known to be lethal. Among various molecular mechanisms proposed so far, perturbation in redox state due to imbalance between radical generation and antioxidant defence is promising. These molecular events are als...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680518/ https://www.ncbi.nlm.nih.gov/pubmed/29078168 http://dx.doi.org/10.1016/j.redox.2017.10.013 |