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Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway

The glyoxalase pathway functions to detoxify reactive dicarbonyl compounds, most importantly methylglyoxal. The glyoxalase pathway is an antioxidant defense mechanism that is essential for neuroprotection. Excessive concentrations of methylglyoxal have deleterious effects on cells, leading to increa...

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Detalles Bibliográficos
Autores principales: Frandsen, Joel R., Narayanasamy, Prabagaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680520/
https://www.ncbi.nlm.nih.gov/pubmed/29080525
http://dx.doi.org/10.1016/j.redox.2017.10.015