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Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway
The glyoxalase pathway functions to detoxify reactive dicarbonyl compounds, most importantly methylglyoxal. The glyoxalase pathway is an antioxidant defense mechanism that is essential for neuroprotection. Excessive concentrations of methylglyoxal have deleterious effects on cells, leading to increa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680520/ https://www.ncbi.nlm.nih.gov/pubmed/29080525 http://dx.doi.org/10.1016/j.redox.2017.10.015 |