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Age-related gene expression in luminal epithelial cells is driven by a microenvironment made from myoepithelial cells
Luminal epithelial cells in the breast gradually alter gene and protein expression with age, appearing to lose lineage-specificity by acquiring myoepithelial-like characteristics. We hypothesize that the luminal lineage is particularly sensitive to microenvironment changes, and age-related microenvi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680554/ https://www.ncbi.nlm.nih.gov/pubmed/29016359 http://dx.doi.org/10.18632/aging.101298 |