Cargando…

Age-related gene expression in luminal epithelial cells is driven by a microenvironment made from myoepithelial cells

Luminal epithelial cells in the breast gradually alter gene and protein expression with age, appearing to lose lineage-specificity by acquiring myoepithelial-like characteristics. We hypothesize that the luminal lineage is particularly sensitive to microenvironment changes, and age-related microenvi...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyano, Masaru, Sayaman, Rosalyn W., Stoiber, Marcus H., Lin, Chun-Han, Stampfer, Martha R., Brown, James B., LaBarge, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680554/
https://www.ncbi.nlm.nih.gov/pubmed/29016359
http://dx.doi.org/10.18632/aging.101298