Cargando…

SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy

The stress-responsive mitochondrial sirtuin SIRT4 controls cellular energy metabolism in a NAD(+)-dependent manner and is implicated in cellular senescence and aging. Here we reveal a novel function of SIRT4 in mitochondrial morphology/quality control and regulation of mitophagy. We report that mode...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lang, Alexander, Anand, Ruchika, Altinoluk-Hambüchen, Simone, Ezzahoini, Hakima, Stefanski, Anja, Iram, Afshin, Bergmann, Laura, Urbach, Jennifer, Böhler, Philip, Hänsel, Jan, Franke, Manuel, Stühler, Kai, Krutmann, Jean, Scheller, Jürgen, Stork, Björn, Reichert, Andreas S., Piekorz, Roland P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680561/ https://www.ncbi.nlm.nih.gov/pubmed/29081403 http://dx.doi.org/10.18632/aging.101307

Ejemplares similares

Correction: SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy
por: Lang, Alexander, et al.
Publicado: (2018)

Subcellular Localization and Mitotic Interactome Analyses Identify SIRT4 as a Centrosomally Localized and Microtubule Associated Protein
por: Bergmann, Laura, et al.
Publicado: (2020)

MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4
por: Lang, Alexander, et al.
Publicado: (2016)

Novel role of the SIRT4-OPA1 axis in mitochondrial quality control
por: Lang, Alexander, et al.
Publicado: (2017)

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations
por: Liao, Chunyan, et al.
Publicado: (2017)

Berberine mitigates hepatic insulin resistance by enhancing mitochondrial architecture via the SIRT1/Opa1 signalling pathway: Berberine mitigates hepatic insulin resistance via SIRT1/Opa1
por: Xu, Jia, et al.
Publicado: (2022)

Irisin activates Opa1-induced mitophagy to protect cardiomyocytes against apoptosis following myocardial infarction
por: Xin, Ting, et al.
Publicado: (2020)

Gα(i3) signaling is associated with sexual dimorphic expression of the clock-controlled output gene Dbp in murine liver
por: Singh, Madhurendra, et al.
Publicado: (2018)

SIRT5 regulation of ammonia-induced autophagy and mitophagy
por: Polletta, Lucia, et al.
Publicado: (2015)

Opa: up and running
por: Binsztok, Henri, et al.
Publicado: (2013)

MCU Up‐regulation contributes to myocardial ischemia‐reperfusion Injury through calpain/OPA‐1–mediated mitochondrial fusion/mitophagy Inhibition
por: Guan, Lichun, et al.
Publicado: (2019)

Liraglutide repairs the infarcted heart: The role of the SIRT1/Parkin/mitophagy pathway
por: Qiao, Huiying, et al.
Publicado: (2018)

Berberine suppressed sarcopenia insulin resistance through SIRT1-mediated mitophagy
por: Su, Xiaojuan, et al.
Publicado: (2023)

Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylation
por: MacVicar, Thomas D. B., et al.
Publicado: (2014)

Melatonin Attenuates Calcium Deposition from Vascular Smooth Muscle Cells by Activating Mitochondrial Fusion and Mitophagy via an AMPK/OPA1 Signaling Pathway
por: Chen, Wei Ren, et al.
Publicado: (2020)

Construction of Opa-Positive and Opa-Negative Strains of Neisseria meningitidis to Evaluate a Novel Meningococcal Vaccine
por: Sadarangani, Manish, et al.
Publicado: (2012)

Matrine alleviates cisplatin‐induced acute kidney injury by inhibiting mitochondrial dysfunction and inflammation via SIRT3/OPA1 pathway
por: Yuan, Lu, et al.
Publicado: (2022)

Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia
por: Qiao, Aimin, et al.
Publicado: (2016)

Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis
por: Guo, Yuanyuan, et al.
Publicado: (2021)

OPA1’s shortcut to mitochondrial fission
por: Short, Ben
Publicado: (2014)

Correction: Construction of Opa-Positive and Opa-Negative Strains of Neisseria meningitidis to Evaluate a Novel Meningococcal Vaccine
por: Sadarangani, Manish, et al.
Publicado: (2013)

Validating the RedMIT/GFP-LC3 Mouse Model by Studying Mitophagy in Autosomal Dominant Optic Atrophy Due to the OPA1Q285STOP Mutation
por: Diot, Alan, et al.
Publicado: (2018)

Two novel compound heterozygous mutations in OPA3 in two siblings with OPA3-related 3-methylglutaconic aciduria
por: Lam, Christina, et al.
Publicado: (2014)

Yap regulates gastric cancer survival and migration via SIRT1/Mfn2/mitophagy
por: Yan, Hongzhu, et al.
Publicado: (2018)

Correction: Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia
por: Qiao, Aimin, et al.
Publicado: (2018)

Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells
por: Anand, Ruchika, et al.
Publicado: (2016)

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
por: Anand, Ruchika, et al.
Publicado: (2014)

Modulation of Mitochondrial Membrane Potential and ROS Generation by Nicotinamide in a Manner Independent of SIRT1 and Mitophagy
por: Song, Seon Beom, et al.
Publicado: (2017)

Transcriptional Regulation of opaR, qrr2–4 and aphA by the Master Quorum-Sensing Regulator OpaR in Vibrio parahaemolyticus
por: Zhang, Yiquan, et al.
Publicado: (2012)

Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency
por: Kushnareva, Y, et al.
Publicado: (2016)

Common Principles and Specific Mechanisms of Mitophagy from Yeast to Humans
por: Kumar, Rajesh, et al.
Publicado: (2021)

Sensitive and Rapid HPLC Method for Determination of Memantine in Human Plasma Using OPA Derivatization and Fluorescence Detection: Application to Pharmacokinetic Studies
por: Zarghi, Afshin, et al.
Publicado: (2010)

Development and Validation of an HPLC Method for Determination of Amifostine and/or Its Metabolite (WR-1065) In Human Plasma Using OPA Derivatization and UV Detection
por: Samiei, Nasim, et al.
Publicado: (2015)

The Effect of OPA1 on Mitochondrial Ca(2+) Signaling
por: Fülöp, László, et al.
Publicado: (2011)

Mitochondrial Membrane Dynamics—Functional Positioning of OPA1
por: Lee, Hakjoo, et al.
Publicado: (2018)

OPA1, a molecular regulator of dilated cardiomyopathy
por: Chen, Jiaqi, et al.
Publicado: (2023)

First report of OPA1 screening in Greek patients with autosomal dominant optic atrophy and identification of a previously undescribed OPA1 mutation
por: Kamakari, Smaragda, et al.
Publicado: (2014)

Irisin Promotes Osteogenesis by Modulating Oxidative Stress and Mitophagy through SIRT3 Signaling under Diabetic Conditions
por: Li, Guangyue, et al.
Publicado: (2022)

SIRT5 Activation and Inorganic Phosphate Binding Reduce Cancer Cell Vitality by Modulating Autophagy/Mitophagy and ROS
por: Barreca, Federica, et al.
Publicado: (2023)

Novel Applications for Oxalate-Phosphate-Amine Metal-Organic-Frameworks (OPA-MOFs): Can an Iron-Based OPA-MOF Be Used as Slow-Release Fertilizer?
por: Anstoetz, Manuela, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_r7rvdpd6atfhttrln27rv973gv