CD10(−)/ALDH(−) cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy

It is long established that tumour-initiating cancer stem cells (CSCs) possess chemoresistant properties. However, little is known of the mechanisms involved, particularly with respect to the organisation of CSCs as stem-progenitor-differentiated cell hierarchies. Here we aimed to elucidate the rela...

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Detalles Bibliográficos
Autores principales: Ffrench, Brendan, Gasch, Claudia, Hokamp, Karsten, Spillane, Cathy, Blackshields, Gordon, Mahgoub, Thamir Mahmoud, Bates, Mark, Kehoe, Louise, Mooney, Aoibhinn, Doyle, Ronan, Doyle, Brendan, O'Donnell, Dearbhaile, Gleeson, Noreen, Hennessy, Bryan T, Stordal, Britta, O'Riain, Ciaran, Lambkin, Helen, O'Toole, Sharon, O'Leary, John J, Gallagher, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680566/
https://www.ncbi.nlm.nih.gov/pubmed/29048400
http://dx.doi.org/10.1038/cddis.2017.379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680566/
https://www.ncbi.nlm.nih.gov/pubmed/29048400
http://dx.doi.org/10.1038/cddis.2017.379

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