Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine

Chemotherapy drugs interfere with cellular processes to generate genotoxic lesions that activate cell death pathways. Sustained DNA damage induced by these drugs can provoke mutations in surviving non-cancerous cells, potentially increasing the risk of therapy-related cancers. Ligation of death rece...

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Detalles Bibliográficos
Autores principales: Miles, Mark A, Hawkins, Christine J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680576/
https://www.ncbi.nlm.nih.gov/pubmed/28981092
http://dx.doi.org/10.1038/cddis.2017.454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680576/
https://www.ncbi.nlm.nih.gov/pubmed/28981092
http://dx.doi.org/10.1038/cddis.2017.454

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