Cargando…
Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine
Chemotherapy drugs interfere with cellular processes to generate genotoxic lesions that activate cell death pathways. Sustained DNA damage induced by these drugs can provoke mutations in surviving non-cancerous cells, potentially increasing the risk of therapy-related cancers. Ligation of death rece...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680576/ https://www.ncbi.nlm.nih.gov/pubmed/28981092 http://dx.doi.org/10.1038/cddis.2017.454 |