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Secretory stressors induce intracellular death receptor accumulation to control apoptosis

Disruption of the Golgi apparatus can induce a distinct form of programmed cell death that has not been thoroughly characterized. We found that pharmacological application of Golgi stress leads to induction of death receptors (DRs) 4 and 5. DR4 appears to be primarily responsible for the initiation...

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Detalles Bibliográficos
Autores principales: van Raam, Bram J, Lacina, Tamara, Lindemann, Ralph K, Reiling, Jan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680588/
https://www.ncbi.nlm.nih.gov/pubmed/28981087
http://dx.doi.org/10.1038/cddis.2017.466