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NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension
Inflammation is involved in pathogenesis of hypertension. NLRP3 inflammasome activation is a powerful mediator of inflammatory response via caspase-1 activation. The present study was designed to determine the roles and mechanisms of NLRP3 inflammasome in phenotypic modulation and proliferation of v...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680591/ https://www.ncbi.nlm.nih.gov/pubmed/28981106 http://dx.doi.org/10.1038/cddis.2017.470 |