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NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension

Inflammation is involved in pathogenesis of hypertension. NLRP3 inflammasome activation is a powerful mediator of inflammatory response via caspase-1 activation. The present study was designed to determine the roles and mechanisms of NLRP3 inflammasome in phenotypic modulation and proliferation of v...

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Detalles Bibliográficos
Autores principales: Sun, Hai-Jian, Ren, Xing-Sheng, Xiong, Xiao-Qing, Chen, Yun-Zhi, Zhao, Ming-Xia, Wang, Jue-Jin, Zhou, Ye-Bo, Han, Ying, Chen, Qi, Li, Yue-Hua, Kang, Yu-Ming, Zhu, Guo-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680591/
https://www.ncbi.nlm.nih.gov/pubmed/28981106
http://dx.doi.org/10.1038/cddis.2017.470

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