Cargando…

DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway

Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma in adults, characterized by a rapidly increasing painless mass. A novel compound, DCZ3301, was synthesized that exerted direct cytotoxicity against DLBCL cell lines. The effects of DCZ3301 on DLBCL cells in vitro and in vivo a...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Xi, Li, Bo, Xie, Bingqian, Xu, Zhijian, Chang, Gaomei, Tao, Yi, Zhang, Yong, Chang, Shuaikang, Wang, Yingcong, Yu, Dandan, Xie, Yongsheng, Li, Tingye, Wang, Houcai, Chen, Gege, Hu, Liangning, Hou, Jun, Zhang, Yiwen, Xiao, Wenqin, Gao, Lu, Shi, Jumei, Zhu, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680593/
https://www.ncbi.nlm.nih.gov/pubmed/29022919
http://dx.doi.org/10.1038/cddis.2017.472