Calcium/calmodulin-dependent kinase kinase 2 regulates hematopoietic stem and progenitor cell regeneration

Hematopoietic stem and progenitor cells (HSPCs) are predominantly quiescent in adults, but proliferate in response to bone marrow (BM) injury. Here, we show that deletion of Ca(2+)/calmodulin (CaM)-dependent protein kinase kinase 2 (CaMKK2) promotes HSPC regeneration and hematopoietic recovery follo...

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Detalles Bibliográficos
Autores principales: Racioppi, Luigi, Lento, William, Huang, Wei, Arvai, Stephanie, Doan, Phuong L, Harris, Jeffrey R, Marcon, Fernando, Nakaya, Helder I, Liu, Yaping, Chao, Nelson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680595/
https://www.ncbi.nlm.nih.gov/pubmed/28981105
http://dx.doi.org/10.1038/cddis.2017.474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680595/
https://www.ncbi.nlm.nih.gov/pubmed/28981105
http://dx.doi.org/10.1038/cddis.2017.474

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