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Effect of cell cycle duration on somatic evolutionary dynamics
Cellular checkpoints prevent damage and mutation accumulation in tissue cells. DNA repair is one mechanism that can be triggered by checkpoints and involves temporary cell cycle arrest and thus delayed reproduction. Repair‐deficient cells avoid this delay, which has been argued to lead to a selectiv...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680637/ https://www.ncbi.nlm.nih.gov/pubmed/29151865 http://dx.doi.org/10.1111/eva.12518 |