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A prospective randomized controlled study: Theophylline on oxidative stress and steroid sensitivity in chronic obstructive pulmonary disease patients

OBJECTIVE: Oxidative stress is involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Corticosteroid fails to suppress inflammation and oxidative stress due to steroid resistance. Theophylline has an effect on histone deacetylase (HDAC) activity and improves steroid sensitivit...

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Detalles Bibliográficos
Autores principales: Ranjani, R., Vinotha, A. T. Sathiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680646/
https://www.ncbi.nlm.nih.gov/pubmed/29184823
http://dx.doi.org/10.4103/jphi.JPHI_58_17