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Development of a binary carrier system consisting polyethylene glycol 4000 - ethyl cellulose for ibuprofen solid dispersion

BACKGROUND AND OBJECTIVE: One of the established strategies to improve solubility and dissolution rate of poorly water-soluble drugs is solid dispersion (SD). Polyethylene glycol (PEG) is used as common carrier despite its stability problem which may be overcome by the addition of hydrophobic polyme...

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Detalles Bibliográficos
Autores principales: Alagdar, Gada Sulaiman A., Oo, May Kyaw, Sengupta, Pinaki, Mandal, Uttam Kumar, Jaffri, Julian Md., Chatterjee, Bappaditya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680650/
https://www.ncbi.nlm.nih.gov/pubmed/29184827
http://dx.doi.org/10.4103/jphi.JPHI_54_17