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Interleukin-1β signaling in fenestrated capillaries is sufficient to trigger sickness responses in mice

BACKGROUND: The physiological and behavioral symptoms of sickness, including fever, anorexia, behavioral depression, and weight loss can be both beneficial and detrimental. These sickness responses are triggered by pro-inflammatory cytokines acting on cells within the brain. Previous research demons...

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Detalles Bibliográficos
Autores principales: Gabriel Knoll, J., Krasnow, Stephanie M., Marks, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680784/
https://www.ncbi.nlm.nih.gov/pubmed/29121947
http://dx.doi.org/10.1186/s12974-017-0990-7