Specific detection of soluble EphA2 fragments in blood as a new biomarker for pancreatic cancer

Because membrane type 1-matrix metalloproteinase 1 (MT1-MMP) and erythropoietin-producing hepatocellular receptor 2 (EphA2) expression are upregulated by the Ras/mitogen-activated protein kinase pathway, they are frequently coexpressed in malignant tumors. MT1-MMP cleaves the N-terminal ligand-bindi...

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Detalles Bibliográficos
Autores principales: Koshikawa, Naohiko, Minegishi, Tomoko, Kiyokawa, Hirofumi, Seiki, Motoharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680914/
https://www.ncbi.nlm.nih.gov/pubmed/29072678
http://dx.doi.org/10.1038/cddis.2017.545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680914/
https://www.ncbi.nlm.nih.gov/pubmed/29072678
http://dx.doi.org/10.1038/cddis.2017.545

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