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Glucocorticoid mediates prenatal caffeine exposure-induced endochondral ossification retardation and its molecular mechanism in female fetal rats

Our previous studies discovered that prenatal caffeine exposure (PCE) could induce intrauterine growth retardation (IUGR) and long-bone dysplasia in offspring rats, accompanied by maternal glucocorticoid over-exposure. This study is to explore whether intrauterine high glucocorticoid level can cause...

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Detalles Bibliográficos
Autores principales: Shangguan, Yangfan, Jiang, Hongqiang, Pan, Zhengqi, Xiao, Hao, Tan, Yang, Tie, Kai, Qin, Jun, Deng, Yu, Chen, Liaobin, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680915/
https://www.ncbi.nlm.nih.gov/pubmed/29072695
http://dx.doi.org/10.1038/cddis.2017.546