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Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway

Our previous study showed that Calreticulin (CRT) promoted the development of pancreatic cancer (PC) through ERK/MAPK pathway. We next investigate whether CRT promotes EGF-induced epithelial–mesenchymal transition (EMT) in PC via Integrin/EGFR-ERK/MAPK signaling, which has not been reported yet to o...

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Detalles Bibliográficos
Autores principales: Sheng, Weiwei, Chen, Chuanping, Dong, Ming, Wang, Guosen, Zhou, Jianping, Song, He, Li, Yang, Zhang, Jian, Ding, Shuangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680916/
https://www.ncbi.nlm.nih.gov/pubmed/29072694
http://dx.doi.org/10.1038/cddis.2017.547