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CITED2 affects leukemic cell survival by interfering with p53 activation

CITED2 (CBP/p300-interacting-transactivator-with-an-ED-rich-tail 2) is a regulator of the acetyltransferase CBP/p300 and elevated CITED2 levels are shown in a number of acute myeloid leukemia (AML). To study the in vivo role of CITED2 in AML maintenance, AML cells were transduced with a lentiviral c...

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Detalles Bibliográficos
Autores principales: Mattes, Katharina, Berger, Gerbrig, Geugien, Marjan, Vellenga, Edo, Schepers, Hein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680917/
https://www.ncbi.nlm.nih.gov/pubmed/29072699
http://dx.doi.org/10.1038/cddis.2017.548