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Suppression of BMP-7 by histone deacetylase 2 promoted apoptosis of renal tubular epithelial cells in acute kidney injury

Cisplatin, a highly effective and widely used chemotherapeutic agent, has a major limitation for its nephrotoxicity. Currently, there are no therapies available to treat or prevent cisplatin nephrotoxicity. We recently identified a novel strategy for attenuating its nephrotoxicity in chemotherapy by...

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Detalles Bibliográficos
Autores principales: Ma, Taotao, Huang, Cheng, Xu, Qingqing, Yang, Yang, Liu, Yaru, Meng, Xiaoming, Li, Jun, Ye, Min, Liang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680919/
https://www.ncbi.nlm.nih.gov/pubmed/29072686
http://dx.doi.org/10.1038/cddis.2017.552