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Guanylate-binding protein 2 regulates Drp1-mediated mitochondrial fission to suppress breast cancer cell invasion

Guanylate-binding protein 2 (GBP2) is a member of the large GTPase superfamily that is strongly induced by interferon-γ (IFN-γ). Although the biochemical characteristics of GBP2 have been reported in detail, its biological function has not been thoroughly elucidated to date. To the best of our knowl...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Zhang, Yu, Wu, Wenshuang, Wang, Fang, Liu, Xinyu, Shui, Guanghou, Nie, Chunlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680924/
https://www.ncbi.nlm.nih.gov/pubmed/29072687
http://dx.doi.org/10.1038/cddis.2017.559