SIRT3 protects hepatocytes from oxidative injury by enhancing ROS scavenging and mitochondrial integrity

Evidences of oxidative stress and mitochondrial dysfunction have been recognized in most of clinical and experimental liver diseases. SIRT3, a member of NAD(+)-dependent deacetylases, is mainly localized in mitochondria. So far, the role of SIRT3 in protecting hepatocytes against oxidative stress re...

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Detalles Bibliográficos
Autores principales: Liu, Jingxin, Li, Dan, Zhang, Tian, Tong, Qiang, Ye, Richard Dequan, Lin, Ligen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680927/
https://www.ncbi.nlm.nih.gov/pubmed/29072685
http://dx.doi.org/10.1038/cddis.2017.564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680927/
https://www.ncbi.nlm.nih.gov/pubmed/29072685
http://dx.doi.org/10.1038/cddis.2017.564

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