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SIRT3 protects hepatocytes from oxidative injury by enhancing ROS scavenging and mitochondrial integrity
Evidences of oxidative stress and mitochondrial dysfunction have been recognized in most of clinical and experimental liver diseases. SIRT3, a member of NAD(+)-dependent deacetylases, is mainly localized in mitochondria. So far, the role of SIRT3 in protecting hepatocytes against oxidative stress re...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680927/ https://www.ncbi.nlm.nih.gov/pubmed/29072685 http://dx.doi.org/10.1038/cddis.2017.564 |