The spontaneous differentiation and chromosome loss in iPSCs of human trisomy 18 syndrome

Aneuploidy including trisomy results in developmental disabilities and is the leading cause of miscarriages in humans. Unlike trisomy 21, pathogenic mechanisms of trisomy 18 remain unclear. Here, we successfully generated induced pluripotent stem cells (iPSCs) from human amniotic fluid cells (AFCs)...

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Detalles Bibliográficos
Autores principales: Li, Ting, Zhao, Hanzhi, Han, Xu, Yao, Jiaying, Zhang, Lingling, Guo, Ying, Shao, Zhen, Jin, Ying, Lai, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680928/
https://www.ncbi.nlm.nih.gov/pubmed/29072700
http://dx.doi.org/10.1038/cddis.2017.565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680928/
https://www.ncbi.nlm.nih.gov/pubmed/29072700
http://dx.doi.org/10.1038/cddis.2017.565

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