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Simultaneous Transplantation of Fetal Ventral Mesencephalic Tissue and Encapsulated Genetically Modified Cells Releasing GDNF in a Hemi-Parkinsonian Rat Model of Parkinson’s Disease

Transplantation of fetal ventral mesencephalic (VM) neurons for Parkinson’s disease (PD) is limited by poor survival and suboptimal integration of grafted tissue into the host brain. In a 6-hydroxydopamine rat model of PD, we investigated the feasibility of simultaneous transplantation of rat fetal...

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Detalles Bibliográficos
Autores principales: Perez-Bouza, Alberto, Di Santo, Stefano, Seiler, Stefanie, Meyer, Morten, Andereggen, Lukas, Huber, Alexander, Guzman, Raphael, Widmer, Hans R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680950/
https://www.ncbi.nlm.nih.gov/pubmed/29113462
http://dx.doi.org/10.1177/0963689717721202