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Ex vivo Pretreatment of Islets with Mitomycin C: Reduction in Immunogenic Potential of Islets by Suppressing Secretion of Multiple Chemotactic Factors

Strategies to reduce the immunogenicity of pancreatic islets and to prevent the activation of proinflammatory events are essential for successful islet engraftment. Pretransplant islet culture presents an opportunity for preconditioning to improve outcomes of islet transplantation. We previously dem...

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Detalles Bibliográficos
Autores principales: Sato, Naoya, Haga, Junichiro, Anazawa, Takayuki, Kenjo, Akira, Kimura, Takashi, Wada, Ikuo, Mori, Tsutomu, Marubashi, Shigeru, Gotoh, Mitsukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680981/
https://www.ncbi.nlm.nih.gov/pubmed/28901184
http://dx.doi.org/10.1177/0963689717721233