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Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity

OBJECTIVE: Glucagon-like peptides are co-released from enteroendocrine L cells in the gut and preproglucagon (PPG) neurons in the brainstem. PPG-derived GLP-1/2 are probably key neuroendocrine signals for the control of energy balance and glucose homeostasis. The objective of this study was to deter...

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Detalles Bibliográficos
Autores principales: Shi, Xuemei, Chacko, Shaji, Li, Feng, Li, Depei, Burrin, Douglas, Chan, Lawrence, Guan, Xinfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681239/
https://www.ncbi.nlm.nih.gov/pubmed/29107283
http://dx.doi.org/10.1016/j.molmet.2017.08.009