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An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism

OBJECTIVE: Strategies improving skeletal muscle mitochondrial capacity are commonly paralleled by improvements in (metabolic) health. We and others previously identified microRNAs regulating mitochondrial oxidative capacity, but data in skeletal muscle are limited. Therefore, the present study aimed...

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Detalles Bibliográficos
Autores principales: Dahlmans, Dennis, Houzelle, Alexandre, Andreux, Pénélope, Jörgensen, Johanna A., Wang, Xu, de Windt, Leon J., Schrauwen, Patrick, Auwerx, Johan, Hoeks, Joris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681243/
https://www.ncbi.nlm.nih.gov/pubmed/29107290
http://dx.doi.org/10.1016/j.molmet.2017.08.007