Multi-polygenic score approach to trait prediction

A primary goal of polygenic scores, which aggregate the effects of thousands of trait-associated DNA variants discovered in genome-wide association studies (GWASs), is to estimate individual-specific genetic propensities and predict outcomes. This is typically achieved using a single polygenic score...

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Detalles Bibliográficos
Autores principales: Krapohl, E, Patel, H, Newhouse, S, Curtis, C J, von Stumm, S, Dale, P S, Zabaneh, D, Breen, G, O'Reilly, P F, Plomin, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681246/
https://www.ncbi.nlm.nih.gov/pubmed/28785111
http://dx.doi.org/10.1038/mp.2017.163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681246/
https://www.ncbi.nlm.nih.gov/pubmed/28785111
http://dx.doi.org/10.1038/mp.2017.163

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