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Early decreased TLR2 expression on monocytes is associated with their reduced phagocytic activity and impaired maturation in a porcine polytrauma model

In their post-traumatic course, trauma patients suffering from multiple injuries have a high risk for immune dysregulation, which may contribute to post-injury complications and late mortality. Monocytes as specific effector cells of the innate immunity play a crucial role in inflammation. Using the...

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Detalles Bibliográficos
Autores principales: Schimunek, Lukas, Serve, Rafael, Teuben, Michel P. J., Störmann, Philipp, Auner, Birgit, Woschek, Mathias, Pfeifer, Roman, Horst, Klemens, Simon, Tim-P., Kalbitz, Miriam, Sturm, Ramona, Pape, Hans-C., Hildebrand, Frank, Marzi, Ingo, Relja, Borna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681268/
https://www.ncbi.nlm.nih.gov/pubmed/29125848
http://dx.doi.org/10.1371/journal.pone.0187404