Decreasing CB(1) receptor signaling in Kupffer cells improves insulin sensitivity in obese mice

OBJECTIVE: Obesity-induced accumulation of ectopic fat in the liver is thought to contribute to the development of insulin resistance, and increased activity of hepatic CB(1)R has been shown to promote both processes. However, lipid accumulation in liver can be experimentally dissociated from insuli...

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Detalles Bibliográficos
Autores principales: Jourdan, Tony, Nicoloro, Sarah M., Zhou, Zhou, Shen, Yuefei, Liu, Jie, Coffey, Nathan J., Cinar, Resat, Godlewski, Grzegorz, Gao, Bin, Aouadi, Myriam, Czech, Michael P., Kunos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681272/
https://www.ncbi.nlm.nih.gov/pubmed/29107297
http://dx.doi.org/10.1016/j.molmet.2017.08.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681272/
https://www.ncbi.nlm.nih.gov/pubmed/29107297
http://dx.doi.org/10.1016/j.molmet.2017.08.011

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