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Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolism

OBJECTIVE: Bombesin-like receptor 3 (BRS-3) is an orphan G protein-coupled receptor. Brs3 null mice have reduced resting metabolic rate and body temperature, increased food intake, and obesity. Here we study the role of Brs3 in different neuron types. METHODS: Mice able to undergo Cre recombinase-de...

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Detalles Bibliográficos
Autores principales: Xiao, Cuiying, Piñol, Ramón A., Carlin, Jesse Lea, Li, Cuiling, Deng, Chuxia, Gavrilova, Oksana, Reitman, Marc L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681273/
https://www.ncbi.nlm.nih.gov/pubmed/29107299
http://dx.doi.org/10.1016/j.molmet.2017.08.013